Maternal residential air pollution and placental imprinted gene expression.

ABSTRACT:

Background

Maternal exposure to air pollution is associated with reduced fetal growth, but its relationship with expression of placental imprinted genes (important regulators of fetal growth) has not yet been studied.

Objectives

To examine relationships between maternal residential air pollution and expression of placental imprinted genes in the Rhode Island Child Health Study (RICHS).

Methods

Women-infant pairs were enrolled following delivery between 2009 and 2013. We geocoded maternal residential addresses at delivery, estimated daily levels of fine particulate matter (PM_2.5; n=355) and black carbon (BC; n=336) using spatial-temporal models, and estimated residential distance to nearest major roadway (n=355). Using linear regression models we investigate

SUBMITTER: Kingsley SL 

PROVIDER: S-EPMC5623128 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature