Cost-effectiveness of HPV-based cervical cancer screening in the public health system in Nicaragua.

ABSTRACT:

Objectives

To evaluate the cost-effectiveness of human papillomavirus (HPV) DNA testing (versus Papanicolaou (Pap)-based screening) for cervical cancer screening in Nicaragua.

Design

A previously developed Monte Carlo simulation model of the natural history of HPV infection and cervical cancer was calibrated to epidemiological data from Nicaragua. Cost data inputs were derived using a micro-costing approach in Carazo, Chontales and Chinandega departments; test performance data were from a demonstration project in Masaya department.

Setting

Nicaragua's public health sector facilities.

Participants

Women aged 30-59 years.

Interventions

Screening strategies included (1) Pap testing every 3 years, with referral to colposcopy for women with an atypical squamo

SUBMITTER: Campos NG 

PROVIDER: S-EPMC5623348 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature