Population-based cohort study examining the association between splenectomy and empyema in adults in Taiwan.

ABSTRACT:

Objective

This study aimed to investigate the association between splenectomy and empyema in Taiwan.

Methods

A population-based cohort study was conducted using the hospitalisation dataset of the Taiwan National Health Insurance Program. A total of 13 193 subjects aged 20-84 years who were newly diagnosed with splenectomy from 2000 to 2010 were enrolled in the splenectomy group and 52 464 randomly selected subjects without splenectomy were enrolled in the non-splenectomy group. Both groups were matched by sex, age, comorbidities and the index year of undergoing splenectomy. The incidence of empyema at the end of 2011 was calculated. A multivariable Cox proportional hazards regression model was used to estimate the HR with 95% CI of empyema associated with splenectomy and oth

SUBMITTER: Lin HF 

PROVIDER: S-EPMC5623461 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature