Association between vomiting in the first trimester and preterm birth: a retrospective birth cohort study in Wuhan, China.

ABSTRACT:

Objective

Although vomiting in the first trimester has been reported to be associated with preterm birth (PTB), findings supporting this association remain inconsistent. Our aim was to assess the association between vomiting and PTB, as well as evaluate if the association is modified by pre-pregnancy body mass index (BMI).

Design

A retrospective cohort study.

Setting

Wuhan, a central city of China.

Participants

A total of 317 463 pregnant women who had a live, singleton newborn from 1 January 2010 to 23 May 2016 were enrolled in our study.

Main outcome measure

PTB was defined as gestational age <37 gestational weeks. Gestational age was calculated using reports from mothers based on the first day of their last menstrual period. An ultrasound was routinel

SUBMITTER: Hu R 

PROVIDER: S-EPMC5623485 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature