Perforated appendicitis in patients with schizophrenia: a retrospective cohort study.

ABSTRACT:

Objective

Altered pain sensitivity may affect the outcome of appendicitis in patients with schizophrenia. We aimed to compare the prevalence of perforation in appendicitis between patients with and without schizophrenia.

Design

Retrospective cohort study with random matching.

Setting

A single tertiary medical centre in Japan.

Participants

From 1985 to 2013, 1821 cases of appendicitis requiring appendectomy were collected. Patients with schizophrenia and a cohort of randomly selected control subjects without schizophrenia who underwent appendectomy were identified.

Primary and secondary outcome measures

The primary outcome was the rate of perforated appendicitis in patients with and without schizophrenia. Secondary outcome was the odds of perforated appen

SUBMITTER: Nishihira Y 

PROVIDER: S-EPMC5623499 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature