New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey.

ABSTRACT:

Objective

Recent clinical studies have shown that anticoagulant therapy might be effective only in specific at-risk subgroups of patients with sepsis and coagulation dysfunction. The definition of sepsis was recently modified, and as such, old scoring systems may no longer be appropriate for the diagnosis of sepsis-associated coagulopathy. The aim of this study was to evaluate prognostic factors in patients diagnosed with sepsis and coagulopathy according to the new sepsis definition and assess their accuracy in comparison with existing models.

Design

Retrospective analysis of the nationwide survey for recombinant human soluble thrombomodulin.

Setting

General emergency and critical care centres in secondary and tertiary care hospitals.

Participants

We evaluated

SUBMITTER: Iba T 

PROVIDER: S-EPMC5623518 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature