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Exercise for patients with major depression: a systematic review with meta-analysis and trial sequential analysis.


ABSTRACT:

Objectives

To assess the benefits and harms of exercise in patients with depression.

Design

Systematic review DATA SOURCES: Bibliographical databases were searched until 20 June 2017.

Eligibility criteria and outcomes

Eligible trials were randomised clinical trials assessing the effect of exercise in participants diagnosed with depression. Primary outcomes were depression severity, lack of remission and serious adverse events (eg, suicide) assessed at the end of the intervention. Secondary outcomes were quality of life and adverse events such as injuries, as well as assessment of depression severity and lack of remission during follow-up after the intervention.

Results

Thirty-five trials enrolling 2498 participants were included. The effect of exercise versus c

SUBMITTER: Krogh J 

PROVIDER: S-EPMC5623558 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature