Stimulated Raman scattering of polymer nanoparticles for multiplexed live-cell imaging.

ABSTRACT: A novel nanoparticle-based imaging strategy is introduced that couples biocompatible organic nanoparticles and stimulated Raman scattering (SRS) microscopy. Polymer nanoparticles with vibrational labels incorporated were readily prepared for multi-color SRS imaging with excellent photo-stability. The Raman-active polymer dots are nontoxic, rapidly enter various cell types, and are applied in multiplexed cell-type sorting.

SUBMITTER: Hu F 

PROVIDER: S-EPMC5623589 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature