Tailored spiral in-out spectral-spatial water suppression pulses for magnetic resonance spectroscopic imaging.

ABSTRACT:

Purpose

To develop short water suppression sequences for 7 T magnetic resonance spectroscopic imaging, with mitigation of subject-specific transmit RF field ( B1+) inhomogeneity.

Methods

Patient-tailored spiral in-out spectral-spatial saturation pulses were designed for a three-pulse WET water suppression sequence. The pulses' identical spatial subpulses were designed using patient-specific B1+ maps and a spiral in-out excitation k-space trajectory. The subpulse train was weighted by a spectral envelope that was root-flipped to minimize peak RF demand. The pulses were validated in in vivo experiments that acquired high resolution magnetic resonance spectroscopic imaging data, using a crusher coil for fast lipid suppression. Residual water signals and MR spectra were compared

SUBMITTER: Ma J 

PROVIDER: S-EPMC5623606 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature