Accelerated radial diffusion spectrum imaging using a multi-echo stimulated echo diffusion sequence.

ABSTRACT:

Purpose

Diffusion spectrum imaging (DSI) provides us non-invasively and robustly with anatomical details of brain microstructure. To achieve sufficient angular resolution, DSI requires a large number of q-space samples, leading to long acquisition times. This need is mitigated here by combining the beneficial properties of Radial q-space sampling for DSI with a Multi-Echo Stimulated Echo Sequence (MESTIM).

Methods

Full 2D k-spaces for each of several q-space samples, along the same radially outward line in q-space, are acquired in one readout train with one spin and three stimulated echoes. RF flip angles are carefully chosen to distribute spin magnetization over the echoes and the DSI reconstruction is adapted to account for differences in diffusion time among echoes.

Re

SUBMITTER: Baete SH 

PROVIDER: S-EPMC5623607 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature