Phase-Dependent Modulation of Signal Transmission in Cortical Networks through tACS-Induced Neural Oscillations.

ABSTRACT: Oscillatory neural activity is considered a basis of signal transmission in brain networks. However, the causal role of neural oscillations in regulating cortico-cortical signal transmission has so far not been directly demonstrated. To date, due to methodological limitations, studies on the online modulatory mechanisms of transcranial alternating current stimulation (tACS)-induced neural oscillations are confined to the primary motor cortex. To address the causal role of oscillatory activity in modulating cortico-cortical signal transmission, we have established a new method using concurrent tACS, transcranial magnetic stimulation (TMS) and electroencephalography (EEG). Through tACS, we introduced 6-Hz (theta) oscillatory activity in the human dorsolateral prefrontal cortex (DLPFC). Durin

SUBMITTER: Feher KD 

PROVIDER: S-EPMC5624081 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature