Integron Digestive Carriage in Human and Cattle: A "One Health" Cultivation-Independent Approach.

ABSTRACT: Objectives: Dissemination of antimicrobial resistance (AMR) is a global issue that requires the adoption of a "One-Health" approach promoting integration of human and animal health. Besides culture-dependent techniques frequently used for AMR surveillance, cultivation-independent methods can give additional insights into the diversity and reservoir of AMR genetic determinants. Integrons are molecular markers that can provide overall and reliable estimation of AMR dissemination. In this study, considering the "One-Health" approach, we have analyzed the integron digestive carriage from stools of humans and cattle living in a same area and exposed to different antibiotic selection pressures. Methods: Three collections of human [general population (GP) and intensive care unit pat

SUBMITTER: Chainier D 

PROVIDER: S-EPMC5624303 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature