Group B streptococcus (GBS) is an important pathogen in human disease- but what about in cystic fibrosis?

ABSTRACT:

Background

Group B Streptococcus (GBS) is a common commensal capable of causing severe invasive infections. Most GBS infections occur in neonates (often as pneumonia). GBS can also cause infection in adults with diabetes and other immunological impairments but rarely leads to pneumonia in adults. GBS has occasionally been found in the sputum of Cystic Fibrosis (CF) patients, an inherited condition known for progressive lung disease. However, the epidemiology and clinical significance of GBS in CF are not understood.

Methods

We retrospectively reviewed a large single-centre adult CF population with an associated comprehensive, prospectively collected bacterial biobank beginning in 1978. We identified all individuals with GBS isolated from their sputum on at least one occasion

SUBMITTER: Skolnik K 

PROVIDER: S-EPMC5625721 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature