Vasorelaxant effects of Angelica decursiva root on isolated rat aortic rings.

ABSTRACT:

Background

Hypertension is one of the most important risk factors for cardiovascular disease (CVD) and a worldwide problem. Despite increases in the development of synthetic drugs for hypertension treatment, the rate of untreated and uncontrolled hypertension remains high. These drugs are effective, but can also cause side effects. Approximately 80% of the world population uses herbal medicines because of their low toxicity and better acceptability by the human body. Therefore, we attempted to identify natural medications for treating hypertension. The 70% ethanol extract of Angelica decursiva root (ADE) shows strong vasorelaxant potential, but no studies have investigated the mechanisms underlying the vasorelaxation effect of A. decursiva.

Methods

Dried root of A. decursiva

SUBMITTER: Kim B 

PROVIDER: S-EPMC5625843 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature