Longitudinal study of the influence of lung function on vascular health from adolescence to early adulthood in a British multiethnic cohort.

ABSTRACT:

Background

Vascular and lung function develop and decline over the life course; both predict cardiovascular events and mortality but little is known of how they develop over time. We analysed their relationship in a multiethnic cohort study to test whether lung function from early adolescence to young adulthood affected vascular indices.

Methods

'DASH' (http://dash.sphsu.mrc.ac.uk) included 6643 children aged 11-13 years in 2003; a representative 10% sample (n = 665) participated in a pilot follow-up in 2013. Psychosocial, anthropometric, blood pressure (BP), and lung function measures were collected in both surveys; aortic pulse wave velocity (PWV) and augmentation index (AIx) were measured at aged 21-23 years. Relationships between forced expiratory volume Z-scores in 1 s

SUBMITTER: Lu Y 

PROVIDER: S-EPMC5625963 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature