The impact of cardiovascular risk factors on cardiac structure and function: Insights from the UK Biobank imaging enhancement study.

ABSTRACT:

Aims

The UK Biobank is a large-scale population-based study utilising cardiovascular magnetic resonance (CMR) to generate measurements of atrial and ventricular structure and function. This study aimed to quantify the association between modifiable cardiovascular risk factors and cardiac morphology and function in individuals without known cardiovascular disease.

Methods

Age, sex, ethnicity (non-modifiable) and systolic blood pressure, diastolic blood pressure, smoking status, exercise, body mass index (BMI), high cholesterol, diabetes, alcohol intake (modifiable) were considered important cardiovascular risk factors. Multivariable regression models were built to ascertain the association of risk factors on left ventricular (LV), right ventricular (RV), left atrial (LA) and

SUBMITTER: Petersen SE 

PROVIDER: S-EPMC5626035 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature