Determination of Cell Membrane Capacitance and Conductance via Optically Induced Electrokinetics.

ABSTRACT: Cell membrane capacitance and conductance are key pieces of intrinsic information correlated with the cellular dielectric parameters and morphology of the plasma membrane; these parameters have been used as electrophysiological biomarkers to characterize cellular phenotype and state, and they have many associated clinical applications. Here, we present our work on the non-invasive determination of cell membrane capacitance and conductance by an optically activated microfluidics chip. The model for determining the cell membrane capacitance and conductance was established by a single layer of the shell-core polarization model. Three-dimensional finite-element analyses of the positive and negative optically induced dielectrophoresis forces generated by the projected light arrays of spots were

SUBMITTER: Liang W 

PROVIDER: S-EPMC5627184 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature