First detection of N1575Y mutation in pyrethroid resistant Anopheles gambiae in Southern Cote d'Ivoire.

ABSTRACT: Background. The intensification of insecticide use for both public health and agriculture in Africa has contributed to growing insecticide resistance. Today, resistance to World Health Organization (WHO)-approved insecticide classes is widespread. In an agricultural area of Southern Côte d'Ivoire, the main malaria vector Anopheles coluzzii shows multiple resistance across insecticides mediated by both target site mutation and metabolic mechanisms. To plan new vector control strategies and avert future resistance liabilities caused by cross-resistance mechanisms extant within populations, it is crucial to monitor the development and spread of both resistance and mechanisms. Methods.  Larvae of Anopheles gambiae were collected from natural breeding sites in Tiassa

SUBMITTER: Edi AVC 

PROVIDER: S-EPMC5627500 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature