Ontology highlight
ABSTRACT:
SUBMITTER: Andorfer MC
PROVIDER: S-EPMC5627516 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
ACS catalysis 20170131 3
The activity of four native FDHs and four engineered FDH variants on 93 low molecular weight arenes was used to generate FDH substrate activity profiles. These profiles provided insights into how substrate class, functional group substitution, electronic activation, and binding impact FDH activity and selectivity. The enzymes studied could halogenate a far greater range of substrates than previously recognized, but significant differences in their substrate specificity and selectivity were obser ...[more]