Vitamin D status and risk for malignant cutaneous melanoma: recent advances.

ABSTRACT: Cutaneous malignant melanoma, whose incidence is increasing steadily worldwide, is the result of complex interactions between individual genetic factors and environmental risk factors. Ultraviolet radiation represents the most important environmental risk factor for the development of skin cancers, including melanoma. Sun exposure and early sunburn during childhood are the principal causes of cutaneous melanoma insurgence in adults, with double the risk relative to a nonexposed population. Consequently, ultraviolet protection has long been recognized as an important measure to prevent such a malignancy. Biological and epidemiological data suggest that vitamin D status could affect the risk of cancer and play a role in cancer prevention by exerting antiproliferative effects. Solar radiation

SUBMITTER: Ombra MN 

PROVIDER: S-EPMC5627529 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature