Evolving patterns in a collaboration network of global R&D on monoclonal antibodies.

ABSTRACT: We investigated the evolution process of collaborative inter-organizational network of the research and development (R&D) on monoclonal antibody (mAb) over the past 30 y. The annual detection of the collaboration network provides dynamics on network structures and relationship changes among different organizations. Our research showed continuous growth of the network's scale and complexity due to the constant entry of new organizations and the forging of new partnering relationships. The evolving topological features reveal a core-periphery structure that became clearer over time and an increasing heterogeneity within the collaborative mAb R&D network. As measured by the number of network participants, dedicated biotechnology firms (DBFs) were the dominant organization form in the field of

SUBMITTER: Kong X 

PROVIDER: S-EPMC5627628 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature