Fluctuation of intraocular pressure in glaucoma patients before and after trabeculectomy with mitomycin C.

ABSTRACT:

Purpose

Intraocular pressure (IOP) fluctuation is considered as a risk factor for glaucoma progression. We investigated IOP values and IOP fluctuation before and after trabeculectomy (TE) with mitomycin C (MMC) measured by 48-hour diurnal-nocturnal-IOP-profiles (DNP).

Methods

Pre- and postoperative DNPs of 92 eyes undergoing primary TE with MMC were analysed. Each 48-hour IOP-profile involved 10 IOP measurements (8:00 a.m., 2:00 p.m., 6:00 p.m., and 9:00 p.m. in sitting and at 00:00 in supine position). The "preoperative DNP" was performed a few weeks before TE. The "postoperative DNP" was performed at least six months (range: 6 months-2 years) after TE. Mean IOP values and IOP fluctuations were calculated.

Results

After TE with MMC mean IOP was reduced from 16.94±3.8

SUBMITTER: Wasielica-Poslednik J 

PROVIDER: S-EPMC5627910 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature