Cytokine polymorphisms are associated with daytime napping in adults living with HIV.

ABSTRACT:

Objective/background

Daytime napping longer than one hour has been associated with an increased risk for all-cause mortality. Associations between cytokine polymorphisms and daytime napping in chronic illnesses such as HIV, however, have not been well described. The purpose of this study was to examine cytokine polymorphisms associated with long daytime napping in adults living with HIV.

Methods

A cross-sectional analysis was conducted using a convenience sample of 257 adults living with HIV. Daytime napping was assessed with wrist actigraphy data collected over three days. Participants categorized as long nappers (≥60 min) were compared to short nappers and non-nappers (<60 min). Single nucleotide polymorphisms (SNPs) for 15 candidate genes involved in cytokine signaling we

SUBMITTER: Byun E 

PROVIDER: S-EPMC5628054 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature