Automatic determination of cardiovascular risk by CT attenuation correction maps in Rb-82 PET/CT.

ABSTRACT:

Background

We investigated fully automatic coronary artery calcium (CAC) scoring and cardiovascular disease (CVD) risk categorization from CT attenuation correction (CTAC) acquired at rest and stress during cardiac PET/CT and compared it with manual annotations in CTAC and with dedicated calcium scoring CT (CSCT).

Methods and results

We included 133 consecutive patients undergoing myocardial perfusion ⁸²Rb PET/CT with the acquisition of low-dose CTAC at rest and stress. Additionally, a dedicated CSCT was performed for all patients. Manual CAC annotations in CTAC and CSCT provided the reference standard. In CTAC, CAC was scored automatically using a previously developed machine learning algorithm. Patients were assigned to a CVD risk category based on their Agatsto

SUBMITTER: Isgum I 

PROVIDER: S-EPMC5628109 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature