Postnatal maturation of the fovea in Macaca mulatta using optical coherence tomography.

ABSTRACT: Changes in the foveal anatomy during infancy are an important component in early development of spatial vision. The present longitudinal study in rhesus monkeys was undertaken to characterize the postnatal maturation of the fovea. Starting at four weeks after birth, the retinas of the left eyes of sixteen infant monkeys were imaged using spectral domain optical coherence tomography (SD OCT). Retinal scans were repeated every 30 days during the first year of life and every 60 days thereafter. Volume scans through the fovea were registered, scaled using a three surface schematic eye, and analyzed to measure foveal pit parameters. The individual layers of the retina were manually segmented and thicknesses were measured over a transverse distance of 1250 microns from the center of the foveal p

SUBMITTER: Patel NB 

PROVIDER: S-EPMC5628152 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature