Efficacy of individualised diets in patients with irritable bowel syndrome: a randomised controlled trial.

ABSTRACT:

Background

Patients with irritable bowel syndrome (IBS) are often placed on diets guided by food intolerance assays, although these have not been validated. We assessed the effects of individualised diets in patients with IBS guided by a leucocyte activation test.

Methods

This is a parallel-group, double-blind, randomised controlled trial of 58 adults with IBS seen at an academic health centre in Northeast USA. Peripheral venous blood was analysed using a leucocyte activation test; individual foods were reported to produce positive or negative results. Participants were randomised to a 4-week diet with either individualised guidance to eliminate foods with positive assay results and allow foods with negative assay results (intervention), or with individualised guidance, matc

SUBMITTER: Ali A 

PROVIDER: S-EPMC5628288 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature