Screening and characterization of lactic acid bacterial strains that produce fermented milk and reduce cholesterol levels.

ABSTRACT:

Objective

To screen for and characterize lactic acid bacteria strains with the ability to produce fermented milk and reduce cholesterol levels.

Methods

The strains were isolated from traditional fermented milk in China. In vitro and in vivo evaluation of cholesterol-reduction were used to identify and verify strains of interest. Characteristics were analyzed using spectrophotometry and plate counting assays.

Results

The isolate HLX37 consistently produced fermented milk with strong cholesterol-reducing properties was identified as Lactobacillus plantarum (accession number: KR105940) and was thus selected for further study. The cholesterol reduction by strain HLX37 was 45.84%. The isolates were acid-tolerant at pH 2.5 and bile-tolerant at 0.5% (w/v) in simulated gastri

SUBMITTER: Guan X 

PROVIDER: S-EPMC5628300 | biostudies-literature | 2017 Oct - Dec

REPOSITORIES: biostudies-literature