Respiratory-gated (4D) contrast-enhanced FDG PET-CT for radiotherapy planning of lower oesophageal carcinoma: feasibility and impact on planning target volume.

ABSTRACT:

Background

To assess the feasibility and potential impact on target delineation of respiratory-gated (4D) contrast-enhanced ¹⁸Fluorine fluorodeoxyglucose (FDG) positron emission tomography - computed tomography (PET-CT), in the treatment planning position, for a prospective cohort of patients with lower third oesophageal cancer.

Methods

Fifteen patients were recruited into the study. Imaging included 4D PET-CT, 3D PET-CT, endoscopic ultrasound and planning 4D CT. Target volume delineation was performed on 4D CT, 4D CT with co-registered 3D PET and 4D PET-CT. Planning target volumes (PTV) generated with 4D CT (PTV_4DCT), 4D CT co-registered with 3D PET-CT (PTV_3DPET4DCT) and 4D PET-CT (PTV_4DPETCT) were compared with multiple positiona

SUBMITTER: Scarsbrook A 

PROVIDER: S-EPMC5628433 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature