Effect of a Low-Calorie Diet on Restoration of Normoglycemia in Obese subjects with Type 2 Diabetes.

ABSTRACT:

Introduction

Type 2 diabetes mellitus (T2DM) is considered to be an inevitably progressive disease. Complex therapies add to the financial and psychological burden. Very low-calorie diets (LCDs) are emerging as an option in the management of type 2 diabetes.

Methods

We performed a clinical audit of patients with T2DM who received 12 weeks of LCD.

Results

This case series documents that 6 out of 12 participants (median baseline HbA1c 9%) achieved HbA1c level in nondiabetes range with LCD despite stopping all antidiabetes medications. There was an improvement in serum triglycerides, HDL cholesterol, total cholesterol, C-Reactive protein, urine microalbumin, liver transaminases, liver fat and the indices of insulin resistance, beta cell secretory capacity, and insulin se

SUBMITTER: Bhatt AA 

PROVIDER: S-EPMC5628553 | biostudies-literature | 2017 Sep-Oct

REPOSITORIES: biostudies-literature