Associations between reflux esophagitis and the progression of coronary artery calcification: A cohort study.

ABSTRACT:

Background

Reflux esophagitis (RE) and coronary heart disease (CHD) have common risk factors, including obesity and metabolic syndrome. This study aimed to evaluate the associations between RE and the future CHD risk.

Methods

This retrospective cohort study included 8,221 participants who were ≥20 years old, and who underwent esophagogastroduodenoscopy and coronary computed tomography (CT) scans during the same visit and subsequent CT scans between 2003 and 2013. RE was defined as the presence of at least Los Angeles classification grade A mucosal break. CT scan was used to determine the coronary artery calcium (CAC) scores. CAC progression was defined as an increase in the CAC score on a subsequent CT scan.

Results

RE was present in 984 (12.0%) participants. RE at ba

SUBMITTER: Min YW 

PROVIDER: S-EPMC5628814 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature