Cross-Species Y Chromosome Function Between Malaria Vectors of the <i>Anopheles gambiae</i> Species Complex.

ABSTRACT: Y chromosome function, structure and evolution is poorly understood in many species, including the Anopheles genus of mosquitoes-an emerging model system for studying speciation that also represents the major vectors of malaria. While the Anopheline Y had previously been implicated in male mating behavior, recent data from the Anopheles gambiae complex suggests that, apart from the putative primary sex-determiner, no other genes are conserved on the Y. Studying the functional basis of the evolutionary divergence of the Y chromosome in the gambiae complex is complicated by complete F1 male hybrid sterility. Here, we used an F1 × F0 crossing scheme to overcome a severe bottleneck of male hybrid incompatibilities that enabled us to experimentally purify a genetically labeled

SUBMITTER: Bernardini F 

PROVIDER: S-EPMC5629335 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature