Genomic diversity and phylogeography of norovirus in China.

ABSTRACT:

Background

Little is known about the phylogeography of norovirus (NoV) in China. In norovirus, a clear understanding for the characteristics of tree topology, migration patterns and its demographic dynamics in viral circulation are needed to identify its prevalence trends, which can help us better prepare for its epidemics as well as develop useful control strategies. The aim of this study was to explore the genetic diversity, temporal distribution, demographic dynamics and migration patterns of NoV that circulated in China.

Results

Our analysis showed that two major genogroups, GI and GII, were identified in China, in which GII.3, GII.4 and GII.17 accounted for the majority with a total proportion around 70%. Our demography inference suggested that during the long-term migr

SUBMITTER: Qiao N 

PROVIDER: S-EPMC5629611 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature