Risks of postextraction bleeding after receiving direct oral anticoagulants or warfarin: a retrospective cohort study.

ABSTRACT:

Objective

The effect of direct oral anticoagulants (DOACs) on the risk of bleeding after tooth extraction remains unclear. This study aimed to evaluate the incidence of postextraction bleeding among patients who received DOAC and vitamin K antagonists (VKAs), such as warfarin.

Design

This study was a retrospective cohort analysis. Incidence rates and propensity score-matched regression models were used to compare the risks of bleeding after tooth extractions involving DOACs and VKAs.

Setting

The study took place in a single university hospital in Japan.

Participants

Between April 2013 and April 2015, 543 patients underwent a total of 1196 simple tooth extractions.

Primary outcome measure

The primary outcome measure was the occurrence of postextraction bl

SUBMITTER: Yagyuu T 

PROVIDER: S-EPMC5629650 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature