Effectiveness of seasonal influenza vaccination in patients with diabetes: protocol for a nested case-control study.

ABSTRACT:

Introduction

Seasonal influenza vaccination (SIV) is recommended for people with diabetes, but its effectiveness has not been demonstrated. All of the available studies are observational and marred with the healthy vaccine bias, that is, bias resulting from the generally better health behaviours practised by people who choose to be vaccinated against influenza, compared with those who do not. This protocol is intended to study the effectiveness of SIV in people with treated diabetes and simultaneously to control for bias.

Methods and analyses

This case-control study is nested in a historical cohort and is designed to study vaccine effectiveness (VE) assessed by morbidity, mortality and anti-infective drug use. The cohort will comprise a representative sample of health insura

SUBMITTER: Casanova L 

PROVIDER: S-EPMC5629692 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature