Association between maternal vitamin D deficiency and small for gestational age: evidence from a meta-analysis of prospective cohort studies.

ABSTRACT:

Objective

To determine whether maternal vitamin D deficiency during pregnancy is associated with small for gestational age (SGA).

Methods

A comprehensive literature search of PubMed, the Cochrane Library, Embase, and the Elsevier ScienceDirect library was conducted to identify relevant articles reporting prospective cohort studies in English, with the last report included published in February 2017. Pooled odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were used to evaluate the correlation in a random effects model.

Results

A total of 13 cohort studies were included in this meta-analysis with a sample of 28 285 individuals from seven countries. The pooled overall OR for babies born SGA was 1.588 (95% CI 1.138 to 2.216; p<0.01) for wom

SUBMITTER: Chen Y 

PROVIDER: S-EPMC5629738 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature