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Effect of inspiratory synchronization during pressure-controlled ventilation on lung distension and inspiratory effort.


ABSTRACT:

Background

In pressure-controlled (PC) ventilation, tidal volume (V T) and transpulmonary pressure (P L ) result from the addition of ventilator pressure and the patient's inspiratory effort. PC modes can be classified into fully, partially, and non-synchronized modes, and the degree of synchronization may result in different V T and P L despite identical ventilator settings. This study assessed the effects of three PC modes on V T, P L , inspiratory effort (esophageal pressure-time product, PTPes), and airway occlusion pressure, P 0.1. We also assessed whether P 0.1 can be used for evaluating patient effort.

Methods

Prospective, randomized, crossover physiologic study performe

SUBMITTER: Rittayamai N 

PROVIDER: S-EPMC5630544 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature