HGV&TB: a comprehensive online resource on human genes and genetic variants associated with tuberculosis.

ABSTRACT: Tuberculosis (TB) is an infectious disease caused by fastidious pathogen Mycobacterium tuberculosis. TB has emerged as one of the major causes of mortality in the developing world. Role of host genetic factors that modulate disease susceptibility have not been studied widely. Recent studies have reported few genetic loci that provide impetus to this area of research. The availability of tools has enabled genome-wide scans for disease susceptibility loci associated with infectious diseases. Till now, information on human genetic variations and their associated genes that modulate TB susceptibility have not been systematically compiled. In this work, we have created a resource: HGV&TB, which hosts genetic variations reported to be associated with TB susceptibility in humans. It currently hou

SUBMITTER: Sahajpal R 

PROVIDER: S-EPMC5630898 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature