Mycoplasma pneumoniae Macrolide Resistance in Children in Central Ohio Detected by Sequencing

ABSTRACT: Abstract

Background

Mycoplasma pneumoniae(Mp) is one of the most common causes of LRTI in school aged children, with estimates of up to 20% of cases of community-acquired pneumonia (CAP). Macrolides are the drug of choice for treating Mp infections, but in the last 2 decades there has been emergence of resistance worldwide. Reported rates in USA vary from 3.5 up to 10.8%, but rates in Ohio are unknown. Currently there is no well-established, standardized method for detecting macrolide resistance and antibiotic treatment is empiric because of these limitations. Our goal was to determine the frequency of macrolide resistance in children with Mp respiratory infections in central Ohio.

Methods

A convenience sample of Mp positive PCR identified by our laboratory-developed assa

SUBMITTER: Lanata Piazzon M 

PROVIDER: S-EPMC5630984 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature