Olfaction and incident Parkinson disease in US white and black older adults.

ABSTRACT:

Objective

To investigate olfaction in relation to incident Parkinson disease (PD) in US white and black older adults.

Methods

The study included 1,510 white (mean age 75.6 years) and 952 black (75.4 years) participants of the Health, Aging, and Body Composition study. We evaluated the olfaction of study participants with the Brief Smell Identification Test (BSIT) in 1999-2000. We retrospectively adjudicated PD cases identified through August 31, 2012, using multiple data sources. We used multivariable Cox models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).

Results

During an average of 9.8 years of follow-up, we identified a total of 42 incident PD cases, including 30 white and 12 black participants. Overall, poor sense of smell, as indicated by

SUBMITTER: Chen H 

PROVIDER: S-EPMC5631167 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature