ALA6, a P₄-type ATPase, Is Involved in Heat Stress Responses in Arabidopsis thaliana.

ABSTRACT: Maintaining lipid membrane integrity is an essential aspect of plant tolerance to high temperature. P₄-type ATPases are responsible for flipping and stabilizing asymmetric phospholipids in membrane systems, though their functions in stress tolerance are not entirely clear. Aminophospholipid ATPase6 (ALA6) is a member of the P₄-type ATPase family, which has 12 members in Arabidopsis thaliana. Here, we show that a loss-of-function mutant of ALA6 (ala6) exhibits clear sensitivity to heat stress, including both basal and acquired thermotolerance treatments. Overexpression of ALA6 improves seedling resistance to heat stress, while mutated ALA6 transgenic plants, in which the conserved functional site of the ALA family has a point mutation, are s

SUBMITTER: Niu Y 

PROVIDER: S-EPMC5632816 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature