Prognostic and clinicopathological value of Twist expression in breast cancer: A meta-analysis.

ABSTRACT:

Background

Despite initial indications that the transcription factor Twist could be used as a breast cancer prognostic marker, there still exists some controversy about its reliability. Thus, the aim of the present study was to assess the relationship between Twist expression and prognosis in breast carcinoma.

Materials and methods

We identified eligible studies that reported an association between Twist expression and breast cancer prognosis by searching the literature in PubMed, Embase, the Cochrane Library, and Web of Science databases, through June 5, 2017. Studies investigating Twist protein or mRNA expression as well as reporting survival data in breast cancer were included. The pooled hazard ratio (HR) and odds radio (OR) with a 95% confidence interval (95% CI) were u

SUBMITTER: Qiao W 

PROVIDER: S-EPMC5633195 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature