KinFin: Software for Taxon-Aware Analysis of Clustered Protein Sequences.

ABSTRACT: The field of comparative genomics is concerned with the study of similarities and differences between the information encoded in the genomes of organisms. A common approach is to define gene families by clustering protein sequences based on sequence similarity, and analyze protein cluster presence and absence in different species groups as a guide to biology. Due to the high dimensionality of these data, downstream analysis of protein clusters inferred from large numbers of species, or species with many genes, is nontrivial, and few solutions exist for transparent, reproducible, and customizable analyses. We present KinFin, a streamlined software solution capable of integrating data from common file formats and delivering aggregative annotation of protein clusters. KinFin delivers analyses

SUBMITTER: Laetsch DR 

PROVIDER: S-EPMC5633385 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature