Study of Genetic Association With DCDC2 and Developmental Dyslexia in Hong Kong Chinese Children.

ABSTRACT:

Background

Doublecortin domain-containing 2 (DCDC2) is a doublecortin domain-containing gene family member and the doublecortin domain has been demonstrated to bind to tubulin and enhance microtubule polymerization. It has been associated with developmental dyslexia and this protein family member is thought to function in neuronal migration where it may affect the signaling of primary cilia.

Objectives

The objective of the study is to find out if there is any association of genetic variants of DCDC2 with developmental dyslexia in Chinese children from Hong Kong.

Methods

The dyslexic children were diagnosed as developmental dyslexia (DD) using the Hong Kong Test of Specific Learning Difficulties in Reading and Writing (HKT-SpLD) by the Department of Health, Hong Kong.

SUBMITTER: Waye MMY 

PROVIDER: S-EPMC5633722 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature