Incidence and severity of self-reported chemotherapy side effects in routine care: A prospective cohort study.

ABSTRACT:

Aim

Chemotherapy side effects are often reported in clinical trials; however, there is little evidence about their incidence in routine clinical care. The objective of this study was to describe the frequency and severity of patient-reported chemotherapy side effects in routine care across treatment centres in Australia.

Methods

We conducted a prospective cohort study of individuals with breast, lung or colorectal cancer undergoing chemotherapy. Side effects were identified by patient self-report. The frequency, prevalence and incidence rates of side effects were calculated by cancer type and grade, and cumulative incidence curves for each side effect computed. Frequencies of side effects were compared between demographic subgroups using chi-squared statistics.

Results

SUBMITTER: Pearce A 

PROVIDER: S-EPMC5634543 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature