CSF inflammatory response after intraventricular hemorrhage.

ABSTRACT:

Objective

To investigate the temporal pattern and relevant associations of CSF inflammatory measures after intraventricular hemorrhage (IVH).

Methods

We analyzed prospectively collected CSF cell counts and protein and glucose levels from participants in the Clot Lysis Evaluation of Accelerated Resolution of IVH phase III (CLEAR III) trial. Corrected leukocyte count and cell index were calculated to adjust for CSF leukocytes attributable to circulating blood. Data were chronologically plotted. CSF inflammatory measures (daily, mean, median, maximum, and cases with highest quartile response) were correlated with initial IVH volume, IVH clearance rate, thrombolytic treatment, bacterial infection, and adjudicated clinical outcome at 30 and 180 days.

Results

A total of 11,

SUBMITTER: Fam MD 

PROVIDER: S-EPMC5634667 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature