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Evaluation on Infectivity of Babesia microti to Domestic Animals and Ticks Outside the Ixodes Genus.


ABSTRACT: Babesiosis caused by Babesia microti parasite is an emerging tick borne zoonotic disease that was confirmed recently in China. To understand the epidemiology characteristics of this emerging disease, infectivity of B. microti to domestic animals and ticks outside the genus Ixodes was evaluated in this study. Different domestic animals, chick, pig, goat, dog and the reference host rat were experimentally inoculated with B. microti-infected erythrocytes and the parasite infection was monitored daily by blood smear observation, real-time PCR detection, nested-PCR and special antibody responses during 55 days period. The results showed that rats infected with B. microti showed a typical sustained infection with strongly antibody responses; however, both goats and dogs infected with B. microti

SUBMITTER: Wu J 

PROVIDER: S-EPMC5635051 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature