Population-based Study of Risk Polymorphisms Associated with Vascular Disorders and Dementia.

ABSTRACT:

Introduction

Cardiovascular and neurodegenerative disorders are among the major causes of mortality in the developed countries. Population studies evaluate the genetic risk, i.e. the probability of an individual carrying a specific disease-associated polymorphism. Identification of risk polymorphisms is essential for an accurate diagnosis or prognosis of a number of pathologies.

Aims

The aim of this study was to characterize the influence of risk polymorphisms associated with lipid metabolism, hypertension, thrombosis, and dementia, in a large population of Spanish individuals affected by a variety of brain and vascular disorders as well as metabolic syndrome.

Material & method

We performed a cross-sectional study on 4415 individuals from a widespread regional distrib

SUBMITTER: Teijido O 

PROVIDER: S-EPMC5635648 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature