Effect of statin on progression of symptomatic basilar artery stenosis and subsequent ischemic stroke.

ABSTRACT:

Background and objective

Symptomatic basilar artery stenosis (BAS) is associated with high risk of ischemic stroke recurrence. We aimed to investigate whether statin therapy might prevent the progression of symptomatic BAS and stroke recurrence.

Methods

We retrospectively analyzed the data of patients with acute ischemia with symptomatic BAS, which was assessed using magnetic resonance angiogram (MRA) imaging on admission day, and 1 year later (or the day of the clinical event). The clinical endpoints were recurrent ischemic stroke and its composites, transient ischemic attack, coronary disease, and vascular death.

Results

Of the 153 patients with symptomatic BAS, 114 (74.5%) were treated with a statin after experiencing a stroke. Statin therapy significantly prevente

SUBMITTER: Yum KS 

PROVIDER: S-EPMC5636063 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature