Oral morphine versus ibuprofen administered at home for postoperative orthopedic pain in children: a randomized controlled trial.

ABSTRACT:

Background

Oral morphine for postoperative pain after minor pediatric surgery, while increasingly popular, is not supported by evidence. We evaluated whether oral morphine was superior to ibuprofen for at-home management of children's postoperative pain.

Methods

We conducted a randomized superiority trial comparing oral morphine (0.5 mg/kg) with ibuprofen (10 mg/kg) in children 5 to 17 years of age who had undergone minor outpatient orthopedic surgery (June 2013 to September 2016). Participants took up to 8 doses of the intervention drug every 6 hours as needed for pain at home. The primary outcome was pain, according to the Faces Pain Scale - Revised, for the first dose. Secondary outcomes included additional analgesic requirements, adverse effects, unplanned health care vi

SUBMITTER: Poonai N 

PROVIDER: S-EPMC5636628 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature