Ultrafast compartmentalized relaxation time mapping with linear algebraic modeling.

ABSTRACT:

Purpose

To dramatically accelerate compartmental-average longitudinal (T₁ ) and transverse (T₂ ) relaxation measurements using the minimal-acquisition linear algebraic modeling (SLAM) method, and to validate it in phantoms and humans.

Methods

Relaxation times were imaged at 3 Tesla in phantoms, in the abdomens of six volunteers, and in six brain tumor patients using standard inversion recovery and multi-spin-echo sequences. k-space was fully sampled to provide reference T₁ and T₂ measurements, and SLAM was performed using a limited set of phase encodes from central k-space. Anatomical compartments were segmented on scout images post-acquisition, and SLAM reconstruction was implemented using two algorithms. Compartment-average T

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC5636648 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature